From: Production, characterization and techno-economic evaluation of Aspergillus fusant l-asparaginase
Cost parameters | l-asparaginase producing strains under differing fermentation modes | ||||||||
---|---|---|---|---|---|---|---|---|---|
Protoplast fusant | Aspergillus candidus | Aspergillus sydowii | |||||||
Batch | Fed-batch | Continuous | Batch | Fed-batch | Continuous | Batch | Fed-batch | Continuous | |
Chemicals ($) | 14.8 | 24.5 | 16.8 | 14.8 | 24.5 | 16.8 | 14.8 | 24.5 | 16.8 |
Consumables ($) | 750 | 1150 | 1025 | 750 | 1150 | 1025 | 750 | 1150 | 1025 |
Labour ($50 h−1) | 4900 | 10000 | 15000 | 5000 | 10000 | 15000 | 5000 | 10000 | 15000 |
Sum ($) | 5664.8 | 11174.5 | 16041.8 | 5764.8 | 11174.5 | 16041.8 | 5764.8 | 11174.5 | 16041.8 |
DCW per vessel (g) | 3066.49 | 8122.59 | 6050.065 | 2475.0 | 5294.34 | 4228.25 | 2599.24 | 4677.42 | 3938.45 |
Production cost per DCW ($g−1) | 1.85 | 1.38 | 2.65 | 2.33 | 2.11 | 3.79 | 2.22 | 2.39 | 4.07 |