Table 1 Antimicrobial susceptibility of CERI, VAN, OXA and daptomycin against Gram-positive and Gram-negative pathogens
Strain | CERI (μg/ml)/(μM) | VAN (μg/ml) | DAP (μg/ml) | OXA (μg/mL) | ||||
|---|---|---|---|---|---|---|---|---|
MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | |
S. aureus | ||||||||
ATCC 25923 | 16/28.67 | 32/57.33 | 1 | 1 | 1 | 4 | 0.5 | 2 |
ATCC 29213 | 16/28.67 | 64/114.67 | 2 | 4 | 0.5 | 1 | 0.25 | 2 |
ATCC 43300 | 16/28.67 | 32/57.33 | 2 | 4 | 0.5 | 1 | 32 | 32 |
Newman | 16/28.67 | 32/57.33 | 2 | 1 | 1 | 2 | < 0.125 | 2 |
SAJ1 | 16/28.67 | 32/57.33 | 4 | 4 | 2 | 2 | > 64 | > 64 |
LZB1 | 16/28.67 | 16/28.67 | 1 | 2 | 0.5 | 1 | 0.25 | 0.5 |
RJ-2 | 16/28.67 | 32/57.33 | 1 | 2 | 0.5 | 1 | 8 | 32 |
USA 300 | > 128/ > 229.33 | > 128/ > 229.33 | 2 | 8 | 0.5 | 8 | 16 | 16 |
SA0524 | 16/28.67 | 16/28.67 | 2 | 8 | 1 | 1 | 8 | 8 |
SA2231 | 16/28.67 | 16/28.67 | 2 | 2 | 0.5 | 1 | 8 | 8 |
E. faecalis | ||||||||
ATCC 29212 | 16/28.67 | > 128/ > 229.33 | 4 | 16 | 4 | 8 | – | – |
E. coli | ||||||||
ATCC 25922 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |
K. pneumoniae | ||||||||
ATCC 700603 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |
A. baumannii | ||||||||
ATCC 1195 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |
MDR 1208 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |
MDR 1069 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |
P. aeruginosa | ||||||||
PAO1 | > 128/ > 229.33 | > 128/ > 229.33 | > 128 | > 128 | > 128 | > 128 | – | – |