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AMB Express

Table 2 Comparison of in vitro biological activity between E-rhBMP-2 and C-rhBMP-2

From: Modulation of osteogenic differentiation by Escherichia coli-derived recombinant bone morphogenetic protein-2

E-rhBMP-2

C-rhBMP-2

Relative potency of E-rhBMP-2 based on C-rhBMP-2

Slope

EC50a (ng/mL)

Slope

EC50a (ng/mL)

0.93 ± 0.14

78.6 ± 6.69

1.46 ± 0.13

22.1 ± 2.55

0.306 ± 0.02

  1. aEC50, half-maximal effective concentration, values were calculated by analyzing the results using a 4-parameter curve
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