Harnessing endophytic fungi for biosynthesis of selenium nanoparticles and exploring their bioactivities

Hussein, Heba G.; El-Sayed, El-Sayed R.; Younis, Nahed A.; Hamdy, Abd El Hamid A.; Easa, Saadia M.

doi:10.1186/s13568-022-01408-8

AMB Express

Table 4 Antibacterial activity of SeNPs synthesized by A. quadrilineatus, A. ochraceus, A. terreus, and F. equiseti against different Gram-positive and Gram-negative human pathogenic bacterial strains

From: Harnessing endophytic fungi for biosynthesis of selenium nanoparticles and exploring their bioactivities

SeNPs concentration (µg mL^− 1)		Diameter of inhibition zone (mm)
SeNPs concentration (µg mL^− 1)		E. coli	B. cereus	B. subtilis	S. aureus	P. aeruginosa	K. pneumoniae
A. quadrilineatus	0.0 (C)	0.00^e	0.00^e	0.00^e	0.00^d	0.00^d	0.00^d
	31.25	0.00^e	0.00^e	0.00^e	0.00^d	0.00^d	0.00^d
	62.50	18.00 ± 1.00^d	0.00^e	0.00^e	0.00^d	0.00^d	0.00^d
	125	25.67 ± 0.58^c	12.67 ± 0.58^d	15.00 ± 1.00^d	15.33 ± 0.58^c	0.00^d	0.00^d
	250	36.67 ± 1.54^b	27.00 ± 1.00^c	24.67 ± 1.54^c	28.00 ± 1.00^c	17.67 ± 0.58^c	17.33 ± 2.08^c
	500	52.33 ± 2.08^a	35.67 ± 0.58^b	33.00 ± 1.00^b	43.33 ± 1.54^b	26.00 ± 1.00^b	27.00 ± 1.00^b
	1000	55.00 ± 2.00^a	43.33 ± 2.08^a	40.00 ± 2.00^a	54.00 ± 2.00^a	35.33 ± 1.54^a	38.00 ± 1.00^a
A. ochraceus	0.0 (C)	0.00^e	0.00^e	0.00^e	0.00^d	0.00^d	0.00^d
	31.25	0.00^e	0.00^e	0.00^e	0.00^d	0.00^d	0.00^d
	62.50	17.33 ± 2.00^d	0.00^e	0.00^e	0.00^e	0.00^d	0.00^d
	125	23.00 ± 1.00^d	16.33 ± 0.58^d	11.33 ± 1.54^d	17.33 ± 0.58^d	0.00^d	0.00^d
	250	34.00 ± 1.00^c	24.00 ± 1.00^c	18.00 ± 1.00^c	26.00 ± 1.00^c	11.67 ± 2.08^c	11.00 ± 1.00^c
	500	42.00 ± 1.00^b	31.67 ± 2.08^b	24.33 ± 0.58^b	32.00 ± 1.00^b	17.33 ± 0.58^b	17.33 ± 0.58^b
	1000	49.67 ± 0.58^a	39.67 ± 1.54^a	30.67 ± 2.08^a	38.67 ± 2.08^a	24.00 ± 1.00^a	25.00 ± 2.08^a
A. terreus	0.0 (C)	0.00^d	0.00^d	0.00^c	0.00^c	0.00^c	0.00^c
	31.25	0.00^d	0.00^d	0.00^c	0.00^c	0.00^c	0.00^c
	62.50	0.00^d	0.00^d	0.00^c	0.00^c	0.00^c	0.00^c
	125	0.00^d	0.00^d	0.00^c	0.00^c	0.00^c	0.00^c
	250	14.67 ± 0.68^c	14.67 ± 2.08^c	0.00^c	0.00^c	0.00^c	0.00^c
	500	22.00 ± 1.00^b	23.00 ± 2.00^b	17.67 ± 2.08^b	18.33 ± 1.54^b	13.33 ± 2.08^b	14.67 ± 1.54^b
	1000	31.33 ± 2.08^a	32.33 ± 1.00^a	27.00 ± 1.00^a	35.00 ± 2.00^a	21.00 ± 1.00^a	22.00 ± 2.08^a
F. equiseti	0.0 (C)	0.00^e	0.00^e	0.00^e	0.00^e	0.00^e	0.00^e
	31.25	0.00^e	0.00^e	0.00^e	0.00^e	0.00^e	0.00^e
	62.50	0.00^e	0.00^e	0.00^e	0.00^e	0.00^c	0.00^e
	125	0.00^e	0.00^e	0.00^e	0.00^e	0.00^c	0.00^c
	250	14.00 ± 1.00^d	13.67 ± 0.58^d	0.00^e	0.00^e	0.00^c	0.00^e
	500	21.67 ± 1.54^d	19.67 ± 2.08^d	16.00 ± 2.00^b	18.67 ± 1.54^b	15.00 ± 1.00^b	12.33 ± 2.08^b
	1000	30.00 ± 2.00^d	27.00 ± 1.00^d	25.00 ± 1.00^a	26.33 ± 2.08^a	23.00 ± 1.00^a	18.33 ± 1.54^a
Amoxicillin/Clavulanic acid		18.33 ± 2.08	16.67 ± 0.58	17.00 ± 2.00	11.67 ± 1.54	10.00 ± 2.00	13.33 ± 1.54

Amoxicillin/Azithromycin was used at a concentration of 100 µg mL^− 1. Calculated mean is for triplicate measurements from three independent experiments ± SD, ^a − eMeans with different superscripts in the same column for each fungal strain’s nanoparticle are considered statistically different (LSD test, P ≤ 0.05)

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