Alternative use of phage display: phage M13 can remain viable in the intestines of poultry without causing damage

AMB Express

Table 2 Mean daily weight gain of birds (MDWG), mean daily feed consumption (MDFC) and feed conversion (FA) of bords of the line Hy-line W-36® at 1–7 days, 8–35 days and 36–42 days of age

Tratament¹	1–7 days old (g/day)			8–35 days old (g/day)			36–42 days old (g/day)
Tratament¹	MDWG	MDFC²	FA²	MDWG	MDFC²	FA²	MDWG	MDFC²	FA²
G 1	14.29	19.80	1.39	31.76	46.20	1.45	57.37	139.46	2.43
G 2	15.59	19.83	1.27	30.64	46.16	1.51	59.78	132.89	2.22
G 3	15.61	19.58	1.25	30.00	50.74	1.69	47.87	132.43	2.77
G 4	14.97	20.42	1.36	27.88	41.10	1.47	68.09	117.17	1.72
G 5	15.86	18.89	1.19	31.16	45.04	1.45	61.99	135.17	2.18
Mean	15.26	19.70	1.29	30.29	45.85	1.51	59.02	131.42	2.26
CV (%)³	9.37	–	–	9.69	–	–	7.66	–	–
P-valor⁴	0.21	–	–	0.64	–	–	0.51	–	–

G1: group inoculated with phage M13. G2: Group inoculated with E. coli ER2738 infected by the phage M13; G3: Group infected by E. coli ER2738; G4: Group inoculated with PEG; G5: Group inoculated with PBS. The birds of G1 were inoculated at all ages (10 PFUs/bird). The birds of G3 were inoculated at 2 days (5.04 log CFU/animal), 8 days (6.64 log CFU/animal) and 15 days of age (6.69 log CFU/animal). ¹Means corresponding to the experimental treatments; ²MDFC and FA data are descriptive only; ³CV (%) corresponds to the coefficient of variation; ⁴Statistical probability; no differences were found for the MDWG variable (P > 0.05) by the Tukey test