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Table 6 Cytotoxic effect of the methanolic extract of S. mahagoni (L.) leaves

From: Chemical characterization, antimicrobial, antioxidant, and cytotoxic potentials of Swietenia mahagoni

Methanolic extract of S. mahagoni (L.) leaves

IC50 (µg/mL)

Remarks

HCT-116

44.2

92.3% at 100 ppm

BJ-1

–

20.4% at 100 ppm

Adriamycin (doxorubicin) [Mw = 579.99]

37.6

IC50 at 65.1 µM

DMSO

–

1% at 100 ppm

Negative control (cells only)

–

0%

  1. IC50 = lethal sample concentration that caused the death of 50% of cells in 48 h