Table 1 Antimicrobial activity of Phoma metabolites
From: Promising antimicrobials from Phoma spp.: progress and prospects
Species | Compound | Activity | Host plant/Source | Reference |
|---|---|---|---|---|
Phoma sp. | Sclerodione | Antifungal: Eurotium repens Ustilago violacea | Hussain et al. (2015) | |
8,9-dihydro-3,5,7-trihydroxy-1,8,8,9-tetramethyl-5-(2-oxopropyl)-4H-phena-leno[1,2-b]furan-4,6(5H)-dione | Antifungal: Mycotypha microspora | Hussain et al. (2015) | ||
Atrovenetinone | Antifungal: Fusarium oxysporum E. repens Ustilago violacea | Hussain et al. (2015) | ||
sclerodin; 8,9-dihydro-3,5,7-trihydroxy-1,8,8,9-tetramethyl-5-(2-oxopropyl)-4H-phenaleno[1,2-b]furan-4,6(5H)-dione, atrovenetinone; and sclerodione | Antibacterial: Bacillus megaterium | Hussain et al. (2015) | ||
Phoma sp. | 4-acetylpyrenophorol | Antibacterial: E. coli, B. megaterium Antifungal: Microbotryum violaceum Antialgal: Chlorella fusca | Lycium intricatum | Zhang et al. (2008) |
4α-acetyldihyd- ropyrenophorin | ||||
cis-dihydropyrenophorin | ||||
tetrahydropyrenophorin | ||||
7α-acetyl- seco-dihydropyrenophorin | ||||
seco-dihydropyrenophorin | Antibacterial: E. Coli, B. megaterium Antifungal: M. violaceum | |||
seco-dihydropyrenopho- rin-1,4-lactone | ||||
pyrenophorin | Antifungal: Microbotryum violaceum Antialgal: C. fusca | |||
4,4⬘- diacetylpyrenophorol | ||||
Phoma sp. URM 7221 | Antibacterial: S. aureus, B. subtilis | Schinus terebinthifolius | da Silva et al. (2017) | |
Phoma sp. | viridicatol, tenuazonic acid, alternariol, and alternariol monomethyl ether | Antifungal: Fusarium graminearum, F lateritium, F. sporotrichioides, F avenaceum, Trichoderma longibrachiatum, Aspergillus flavus and Alternaria alternata | Eleusine coracana | Mousa et al. (2015) |
Phoma sp. | Phomodione | Antifungal: Pythium ultimum, Sclerotinia sclerotiorum, Rhizoctonia solani | Saurauia scaberrinae | Hoffman et al. (2008) |
Antibacterial: S. aureus, E. coli | ||||
Phoma herbarum VB7 | Phalate derivates | Antibacterial: Vibrio cholerae, Micrococcus luteus, Salmonella thyphi, S aureus | Mangrove leaves | Bhimba et al. (2012) |
Phoma sp. | polyketide derivatives | Antibacterial: E. coli, B. subtilis, Mycobacterium phlei,S. aureus | Ectyplasia perox | Elsebai et al. (2016) |
Phoma multirostrata PUTY3 | Crude extract | Antibacterial: Pseudomonas aeruginosa | Carica papaya | Ahmed and Sarma (2020) |
Phoma medicaginis | Crude extract | Antibacterial: S. aureus, E. coli, P. aeruginosa | Mikania cordata | Jayatilake and Munasinghe (2020) |
Phoma hedericola | Antibacterial: B. subtilis, Bacillus licheniformis, Micrococcus luteus, P. aeruginosa | Calotropis procera | Juyal et al. (2017) | |
Phoma sorghina, Phoma exigua, Phoma herbarum, Phoma fimeti | pigments | Antibacterial:S. aureus, P. aeruginosa, B. subtilis and Proteus vulgaris | Kadu (2021) | |
Phoma moricola | (3S)-3, 6, 7-trihydroxy-α-tetralone | Antibacterial: E. coli, Klebsiella pneumoniae, P. vulgaris, P. aeruginosa, Salmonella typhimurium, Staphylococcus aureus, and Streptococcus faecalis | Withania somnifera | Roshan and Mohana (2021) |
Antifungal: Alternaria brassicicola, A. geophila, Aspergillus flavus, A. fumigatus, A. ochraceus, A. tamarii, A. terreus, Curvularia tetramera, F. oxysporum, F. lateritium, F. equiseti, F. udum, verticillioides, Penicillium citrinum, P. expansum | ||||
Phoma sp. | flavipucine | Antifungal:Phytophthora infestans | Salsola oppositifolia | Loesgen et al. (2011) |
Phoma herbarum | Ethyl acetate extract | Antibacterial: Bacillus cereus | Urospermum picroides | El-Zawawy et al. (2020) |
Phoma sp.135 | cryptophomic acid, cryptodiol, cryptotriol | Antibacterial:E. coli, B. subtilis, Mycobacterium phlei, S. aureus | Marine-derived | Elsebai et al. (2018) |
Phoma sp. L28 | 7-(γ,γ)-dimethylallyloxymacrosporin, macrosporin, 7-methoxymacrosporin, tetrahydroaltersolanol B, altersolanol L, ampelanol | Antifungal: Colletotrichum musae, Colletotrichum gloeosporioides, Fusarium graminearum, Penicillium italicum, F. oxysporum. f. sp. lycopersici Rhizoctonia solani | mangrove | Huang et al. (2017) |
macrosporin | Antifungal: F. graminearum | |||
Phoma sp. JS752 | barceloneic acid C | Antibacterial: Listeria monocytogenes, Staphylococcus pseuditermedius | Phragmites communis | Xia et al. (2015) |
Phoma macrostoma | macrooxazole C | Antibacterial: B. subtilis Antifungal: Mucor hiemalis | Circium arvense | Matio Kemkuignou et al. (2020) |
macrocidin A macrooxazole B, macrooxazole C, macrocidin Z | Antibacterial:S. aureus | |||
Phoma herbarum YG5839 | tyrosine derivative, terezine derivatives | Antifungal: F. oxysporum, F. graminearum, P. italicum, Colletotrictum gloeosporioides, Colletotrichum musae | marine-sponge-derived | Hu et al. (2021) |
Phoma eupatorii 8082 | Antifungal: Phytophthora infestans | De Vries et al. (2018) | ||
Phoma multirostrata XJ-2–1 | Ergocytochalasin A | Antiviral: Human dengue virus type 3 (DV3), influenza A virus (H1N1), respiratory syncytial virus (RSV) | Peng et al. (2020) | |
Phoma sp. | Phomalacton, (3R)-5-hydroxymellein, emodin | Antibacterial: Microbotryum violaceum, Bacillus megaterium | Fucus serratus | Hussain et al. (2014) |
Phoma sp. WF4 | Viridicatol, tenuazonic acid, alternariol, alternariol monomethyl ether ( | Antifungal: F. graminearum | Eleusine coracana | Mousa et al. (2015) |
Phoma sp. | Phomapyrrolidones A, B and C | Antibacterial: Mycobacterium tuberculosis | Saurauia scaberrinae | Wijeratne et al. (2013) |
Phoma sp. | 4-hydroxymellein | Antibacterial: B. subtilis | Cinnamomum mollissimum | Santiago et al. (2014) |
4,8-dihydroxy-6-methoxy-3-methyl-3,4-dihydro-1H-isochromen-1-one | Antifungal: Aspergillus niger | |||
Phoma sp. | Thiodiketopiperazine deriva- tives | Antibacterial: S. aureus, Streptococcus pyogenes | Glycyrrhiza glabra | Arora et al. (2016) |
Phoma sp. | phomafungin | Antifungal: Candida albicans, Aspergillus fumigatus, Trichophyton mentagrophytes | Africa and the Indian and Pacific Ocean islands | Herath et al. (2009) |