Skip to main content

Table 2 Reduced combinatorial design and experimental data

From: Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production

No.

TOIa

MOIb

pH

Titer

CSVYc

Foldd

1

4

2

7.0

1.0E + 10

2222

1111

2

4

5

7.0

9.5E + 09

1939

388

3

4

10

7.2

1.2E + 10

2667

267

4

4

15

7.2

1.3E + 10

2453

164

5

8

2

7.2

2.1E + 10

2770

1385

6

8

5

7.2

1.9E + 10

2262

452

7

8

10

7.0

6.6E + 09

821

82

8

12

15

7.0

6.3E + 09

497

33

9

12

2

7.0

5.5E + 09

435

218

10

12

5

7.2

1.6E + 10

1393

279

11

16

10

7.0

4.0E + 09

247

25

12

16

15

7.2

9.5E + 09

590

39

13

16

2

7.2

9.5E + 09

625

313

14

4

2

7.0

8.5E + 09

1574

787

15

8

2

7.2

1.7E + 10

1833

917

16

8

10

7.0

4.6E + 09

575

58

  1. a TOI: time of infection
  2. b MOI: multiplicity of infection
  3. c CSVY: cell-specific virus yield
  4. d Fold: adenovirus fold expansion