From: Development of a perfusion process for serum-free adenovirus vector herpes zoster vaccine production
No. | TOIa | MOIb | pH | Titer | CSVYc | Foldd |
---|---|---|---|---|---|---|
1 | 4 | 2 | 7.0 | 1.0E + 10 | 2222 | 1111 |
2 | 4 | 5 | 7.0 | 9.5E + 09 | 1939 | 388 |
3 | 4 | 10 | 7.2 | 1.2E + 10 | 2667 | 267 |
4 | 4 | 15 | 7.2 | 1.3E + 10 | 2453 | 164 |
5 | 8 | 2 | 7.2 | 2.1E + 10 | 2770 | 1385 |
6 | 8 | 5 | 7.2 | 1.9E + 10 | 2262 | 452 |
7 | 8 | 10 | 7.0 | 6.6E + 09 | 821 | 82 |
8 | 12 | 15 | 7.0 | 6.3E + 09 | 497 | 33 |
9 | 12 | 2 | 7.0 | 5.5E + 09 | 435 | 218 |
10 | 12 | 5 | 7.2 | 1.6E + 10 | 1393 | 279 |
11 | 16 | 10 | 7.0 | 4.0E + 09 | 247 | 25 |
12 | 16 | 15 | 7.2 | 9.5E + 09 | 590 | 39 |
13 | 16 | 2 | 7.2 | 9.5E + 09 | 625 | 313 |
14 | 4 | 2 | 7.0 | 8.5E + 09 | 1574 | 787 |
15 | 8 | 2 | 7.2 | 1.7E + 10 | 1833 | 917 |
16 | 8 | 10 | 7.0 | 4.6E + 09 | 575 | 58 |