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Table 3 GC–MS analysis of the methylene chloride extract of A. flavus AUMC14507

From: Bioprospecting endophytic fungi for bioactive metabolites and use of irradiation to improve their bioactivities

No

RT

(min(

MW

MF

Area

(%)

Detected compounds

Bioactivity

Reference

1

5.05

324

C19H20N2O3

4.63

20-Deethyl-17-oxovincadifformine

Cytotoxic, Antimicrobial

Zhang et al. (2014)

2

5.23

129

C8H19N

1.22

N,N-Bis (isobutyl)amine

Antitumor,

Antimicrobial,

Kumar et al. (2018)

3

5.30

116

C5H8O3

1.44

( +)-(S)-5-Hydroxymethyloxolan-2-one

  

4

6.43

84

C4H8N2

1.10

Acetonitrile, (dimethylamino)- (CAS)

  

5

10.37

386

C18H15ClN4O4

1.13

3-(p-Ethoxyphenyl)-4-[5-(2-chlorophenyl)-dealta.(2)-1,2,4-oxadiazolin-3-yl]sydnone

Antimicrobial

Mallur and Badami (2000)

6

10.65

572

C37H32O6

1.05

(-)-2,2′,3,3′-Tetraethyl-(8-hydroxy-8-methoxy)-7,7′-bi(phenanthrene-1,4-dione)

Cytotoxicity, Antimicrobial

Kovács's et al. (2008)

7

15.94

696

C51H68O

1.11

Bis(3,6-di-tert-butyl-1-azulenyl)(3,5-ditert-butyl-4-hydroxyphenyl)methane

Antibacterial, Antioxidant

Praveen et al. (2015)

8

16.86

692

C44H44N4O4

1.19

N,N-'Dicyclohexyl-1,7-dipyrrolidinylperylene-3,4:9,10-tetracarboxylicacidbisimide

  

9

17.87

658

C44H42N4O2

1.10

2,9-Bis(5-tert-butyl-2-methoxy-3-pyridylphenyl)-1,10-phenanthroline

  

10

17.94

696

C40H56O10

1.24

Nephthoside -1,2′,3′,4′-Tetraacetate

  

11

18.52

656

C36H52N2O9

1.57

Jiufengdine

Drug lead

Zhou et al. (2004)

12

19.40

698

C48H34N4O2

1.65

Cis-5,10-bis(4-formylphenyl)-15,20-di(4′′-tolyl) porphyrine

Photodynamic therapy of tumor

Lamarche and Francois (2002)

13

21.17

659

C34H45NO12

1.10

3-Acetoy-8-deacetoxy-N,19-seco-22-nor-17-(1,2-oxazocyclopropan-1-yl) yunaconitine

Antiinfammatory, Antineoplastic

Zhang et al. (2020)

14

22.00

760

C48H56O8

1.37

Methoxychromene precocene tetramer

  

15

22.05

58

C4H10

1.81

Butane (CAS)

  

16

22.34

206

C13H18O2

4.12

3,4-Dihydro-2H-1,5(3′′-t-butyl) Benzodioxepine

Antioxidant

Zhang et al. (2014)

17

22.86

666

C26H16Cl6O8

1.11

Russuphelol

Cytotoixic

Laus (2001)

18

24.48

636

C18Cl12

1.06

Dodecachloro-3,4-benzo Phenanthrene

Anticancer

Li et al. (2006)

19

26.43

60

C8H17NO

1.40

2-[N-(tButylamino)]-2-methylpropanal

  

20

26.68

618

C39H54O6

1.24

2-Hydroxy-3-methoxy-6,7,10,11-tetrapentyloxytriphenylene

  

21

30.89

270

C17H34O2

10.18

Hexadecanoic acid, methyl ester (CAS)

Antibacterial

Astiti and Ramona (2021)

22

31.62

678

C36H40Cl2N4O5

1.08

2,4-bis(2-chloroethyl)-8-h ydroxymethyl)-6,7-bis[2-(methoxycarbonyl) ethyl]-1,3,5-trimethylporphyrin

Photodynamic therapy of tumor

Lamarche et al. (2002)

23

32.77

111

C5H5NO2

1.06

3-Deazauracil

Antiviral,Anticancer

Ogilvie et al. (1984)

24

34.03

294

C19H34O2

4.90

9,12-Octadecadienoic acid, methyl ester, (E,E)-(CAS)

  

25

34.12

296

C19H36O2

18.08

9-Octadecenoicacid,methyl ester, (E)-(CAS)

Anticancer

Ahamed et al. (2020)

26

34.58

340

C22H44O2

3.04

Heneicosanoic acid, methyl ester (CAS)

Antimicrobial Antioxidant

Salem et al. (2014)

27

38.46

729

C37H47NO14

1.13

N-De-ethylyunaconitineimine N-oxide

  

28

39.12

670

C48H38N4

1.05

2-Butyl-5,10,15,20- tetraphenylporphyrin

  

29

41.07

486

C27H38N2O6

1.37

4,25-Secoobscurinervan4-ol,25-ethyl-15,16-dimethoxy-,25 acetate,(4á,22à)-

  

30

41.65

144

C9H20O

1.34

3-Ethyl-2-heptanol

  

31

42.06

126

C7H14N2

1.07

6-Cyanohexanamine

  

32

42.14

378

C22H22N2O4

1.12

Isopropyl4,6-dioxo-3,5-diphenyl-perhydropyrrolo[3,4-c] Pyrrole-1-carboxylate

  

33

42.40

696

C40H56O10

1.18

Nephthoside -1,2′,3′,4′-Tetraacetate

Cytotoxic

Antioxidant

Sunassee and Davies-Coleman (2012)

34

42.59

692

C44H44N4O4

1.12

N,N′-Dicyclohexyl-1,7-dipyrrolidinylperylene-3,4:9,10-tetracarboxylic acid bisimide

  

35

43.18

616

C32H40O12

1.06

Anodendroside E 2,monoacetate

Antimicrobial

Abdel-Rahman et al. (2019)

36

44.41

633

C37H44ClNO6

1.21

PENITREM A

Antimicrobial

Anticancer

Sallam et al. (2013)

Amos-Tautua et al. (2020)

37

44.75

692

C44H44N4O4

1.15

N,N′ –Dicyclohexyl-1,7-dipYrrolidinylperylene-3,4:9,10-tetracarboxylic acid bisimide

  

38

47.81

676

C36H60N4O8

1.04

Bis(3,6,9,12-tetraoxapentaethylene)crowno-N,N,N′,N′-tetramethyl-p- phanediamine

  

39

53.65

489

C27H39NO7

1.69

3-Acetoxy-8,9-dehydro-12,13-secopseudaconin-14-one

  

40

54.32

660

C32H40O12

1.61

Anodendroside E 2,monoacetate (CAS)

Antimicrobial

Abdel-Rahman et al. (2019)

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