Table 4 Mathematical modeling and drug release kinetics of RJA and SAC-containing Na alginate emulgel formulation according to zero-order, first-order and Higuchi equations
| Substance | Zero-order | First-order | Higuchi model | Drug release kinetics mechanism |
|---|---|---|---|---|
| RJA | R2 = 0.620 | R2 = 0.909 | R2 = 0.855 | First-order |
| SAC | R2 = 0.735 | R2 = 0.574 | R2 = 0.857 | Higuchi |