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Table 2 Box-Benhnken experiment results for significant factors

From: A systematic study of the production of Monacolin K by solid state fermentation of Monascus ruber

Source Coefficient Sum of squares df Mean squares F-value p-value
Model 14.40 117.92 9 13.10 95.79 < 0.0001**
A 0.85 5.73 1 5.73 41.88 0.0003**
B − 0.26 0.53 1 0.53 3.88 0.0896
C 1.50 17.97 1 17.97 131.38 < 0.0001**
AB 0.82 2.72 1 2.72 19.90 0.0029**
AC 0.55 1.22 1 1.22 8.93 0.0203*
BC 0.62 1.54 1 1.54 11.24 0.0122*
A2 − 3.26 44.64 1 44.64 326.39 < 0.0001**
B2 − 0.88 3.25 1 3.25 23.77 0.0018**
C2 − 2.80 33.04 1 33.04 241.55 < 0.0001**
Residual   0.96 7 0.14   
Lack of fit   0.49 3 0.16 1.39 0.3673
Pure error   0.47 4 0.12   
Core total   118.88 16