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Table 2 The binding affinity of DENV-LPs towards heparin

From: Humoral immune response induced with dengue virus-like particles serotypes 1 and 4 produced in silkworm

Protein

KD (nM)

Ka (M–1)

N

ΔG (kcal mol–1)

Ligand

Host

Method

Refs.

DENV-LP/1CprME

235.2

4.44 × 106

0.88

– 8.92

Heparin

B. mori

ITC

This study

DENV-LP/1prME

952.4

1.05 × 106

0.98

– 9.28

Heparin

B. mori

ITC

This study

DENV-LP/4CprME

197.6

5.06 × 106

1.14

– 8.99

Heparin

B. mori

ITC

This study

DENV-LP/4prME

819.7

1.22 × 106

0.58

– 8.85

Heparin

B. mori

ITC

This study

DENV-2 E protein

5.0

O-sulfated heparin

E. coli

SPR

Marks et al. (2001)

DENV-2 E protein

5.0

N- and O-sulfated heparin

E. coli

SPR

Marks et al. (2001

DENV-2 E protein

15.0

Heparin

COS-7

ITC

Chen et al. (1997)

ZIKV-E

433.0

Heparin

E. coli

SPR

Kim et al. (2017)