Fig. 6
a The interactions between DENV-LPs/1CprME, /1prME, /4CprME and /4prME with mixed sera from dengue patients [rapid diagnostic test NS1(+)] were investigated (Welch t-test, *p < 0.05, **p < 0.01, ***p < 0.001). b Binding reactions were analyzed using direct ELISA as described. Specific IgG generation by DENV-LPs/1CprME, /1prME, /4CprME and /4prME. BALB/c mice were intraperitoneally immunized with 50 μg of monovalent DENV-LPs/1CprME, /1prME, /4CprME and /4prME. At 0, 2 and 4 weeks, sera were collected and used to test for binding of the specific IgG (Welch t-test, *p < 0.05, **p < 0.01, ***p < 0.001)