Fig. 6
From: Small molecule targeting amyloid fibrils inhibits Streptococcus mutans biofilm formation
Effects of D25 on bacterial amyloid fibrils. Fluorescence intensity of free-floating bacterial cells and biofilms were utilized to document effects of D25 on amyloid fibrils. a free-floating bacterial cells. b biofilms. Data were presented as mean  ±  standard deviations from three independent experiments. NS differences were not statistically significant when compared with control group (P  < 0.05). TEM (transmission electron microscopy) images of amyloid fibrils in c free-floating bacterial cells and d biofilms were recorded in the presence or absence of D25. White arrows represented amorphous aggregates and red arrows represented amyloid fibrils. e Free amyloid fibrils and single bacterial cell without obvious amyloid fibrils around were visualized in biofilms by TEM images