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Fig. 5 | AMB Express

Fig. 5

From: Small molecule targeting amyloid fibrils inhibits Streptococcus mutans biofilm formation

Fig. 5

Morphological changes of S. mutans biofilms when treated with or without D25 at the concentration of 6.25 μg/mL. a Confocal images (merged images of dead/live bacteria) showed the inhibitory effects of D25 on S. mutans biofilms (Green, live bacteria, SYTO9; red, dead bacteria, PI). Images were taken at 63 ×  magnification. b Quantification analysis of biomass were evaluated with Comstat 2. *Differences were statistically significant when compared with control group (P  < 0.05). c Architecture of 24-h S. mutans biofilms was documented by scanning electron microscopy. Images were acquired at the magnification of 5000 ×  and 20,000 × . d The morphological changes of single bacterial cell in biofilms were recorded via atomic force microscopy. White arrows represented S. mutans cells

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