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AMB Express
Fig. 3 | AMB Express

Fig. 3

From: Anti-tumor effect of polysaccharide from Pleurotus ostreatus on H22 mouse Hepatoma ascites in-vivo and hepatocellular carcinoma in-vitro model

Fig. 3

Immunomodulatory effects of polysaccharide on H22 malignant ascites mice model A Immunohistochemistry was performed of liver sample tissues to observed Foxp3 and Stat3 expression in mice model and observed a significant decrease in gene expression in a dose-dependent manner. Images were captured at the 40X lens. B Cytokines level was checked by performing Elisa such as IL-2, TNFα, and INFγ was observed to have a significant increase in serum in a dose-dependent manner. C Western blot analysis was performed to observe protein expression of Foxp3 and Stat3 and results show a significant dose-dependent decrease in expression. *p < 0.05, **p < 0.01, ***p ≤ 0.001. *PPO (Polysaccharide from Pleurotus ostreatus), *CTX (Cyclophosphamide)

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