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Table 6 Effect of organic acids on mRNA gene expression in the jejunum and cecal tonsil of broilers with and without coccidial challenge

From: Effect of organic acids on growth performance, intestinal morphology, and immunity of broiler chickens with and without coccidial challenge

Treatments1 C.C2 Jejunum3 Cecal Tonsil3
18d 29d 18d 29d
   CLDN1 ZO-1 OCLN CLDN1 ZO-1 OCLN CLDN1 ZO-1 OCLN CLDN1 ZO-1 OCLN
CON − 1.06 1.14 1.29 1.32 1.14 1.06 1.02 1.09 1.13 1.04 1.01 1.05
OAW − 1.49 2.43 3 1.89 1.4 1.81 2.3 1.45 1.34 1.31 1.41 1.23
OAF − 1.11 1.06 0.72 1.94 1.93 4.03 1.94 2 1.96 0.61 1.04 1.27
CONC  +  1.22 1.24 1.13 0.92 1.22 2.39 1.1 1.35 2.39 0.38 0.71 1.51
OAWC  +  2.04 1.04 0.8 0.97 2.02 4.31 1.52 1.73 1.47 0.83 1.22 1.24
OAFC  +  2.13 1.26 1.43 3.41 0.98 2.66 1.06 1.49 1.52 0.69 0.92 0.87
SEM   0.65 0.591 0.836 0.775 0.365 1.538 0.557 0.304 0.337 0.26 0.225 0.221
Main effect means
 CON   1.14 1.19 1.21 1.12 1.18 1.73 1.06 1.22 1.76 0.71 0.86 1.28
 OAW   1.77 1.73 1.9 1.43 1.71 3.06 1.91 1.59 1.41 1.07 1.32 1.23
 OAF   1.62 1.16 1.08 2.67 1.45 3.34 1.5 1.75 1.74 0.65 0.98 1.07
 C.C − 1.22 1.54 1.67 1.72 1.49 2.3 1.75 1.52 1.48 0.99 1.15 1.18
 +  1.8 1.18 1.12 1.77 1.41 3.12 1.23 1.52 1.79 0.63 0.95 1.21
 P-value Diet 0.61 0.559 0.58 0.128 0.365 0.54 0.331 0.227 0.516 0.235 0.13 0.623
C.C 0.288 0.459 0.432 0.939 0.791 0.519 0.259 0.977 0.262 0.109 0.28 0.901
Diet × C.C 0.802 0.338 0.223 0.287 0.114 0.446 0.641 0.357 0.054 0.358 0.926 0.167
  1. 1CON Control diet, OAW Organic acid in water, OAF Organic acid in feed, CONC Control diet with Coccidial challenge, OAWC Organic acid in water with Coccidial challenge; and OAFC Organic acid in feed with Coccidial challenge
  2. 2C.C = Coccidial Challenge
  3. 3CLDN1 = Claudin1; ZO-1 = Zona Occludin-1; OCLN = Occludin
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