Table 1 Comparison of growth and bioconversion for different initial 1,3-PDO concentrations in shake flask cultures

Final DW (g L⁻¹)

0.18 ± 0.01

0.33 ± 0.02

0.22 ± 0.03

0.12 ± 0.02

Number of generations (N_g)

2.21 ± 0.06

3.17 ± 0.03

2.58 ± 0.09

1.72 ± 0.02

Final 1,3-PDO consumption (%)^a

ND^b

99.4 ± 0.7

53.7 ± 1.3

14.4 ± 1.4

Final 3-HP titre (g L⁻¹)

ND^b

6.02 ± 0.06

3.77 ± 0.61

2.14 ± 0.06

Final 3-HP yield (mol mol⁻¹)

ND^b

1.07 ± 0.03

0.59 ± 0.10

0.59 ± 0.01

Final 3-HPA titre (g L⁻¹)

ND^b

0.16 ± 0.00

1.06 ± 0.06

0.55 ± 0.03

Final 3-HPA yield (mol mol⁻¹)

ND^b

0.04 ± 0.00

0.21 ± 0.01

0.19 ± 0.01

Final pH

6.7 ± 0.08

4.29 ± 0.05

4.44 ± 0.13

5.11 ± 0.17

µ_max (h⁻¹)

0.21 ± 0.01

0.28 ± 0.004

0.29 ± 0.01

0.27 ± 0.01

Normalised RMSE

2%

1%

2%

3%