Antibiotic resistance, virulence-associated genes analysis and molecular typing of Klebsiella pneumoniae strains recovered from clinical samples

Mirzaie, Amir; Ranjbar, Reza

doi:10.1186/s13568-021-01282-w

AMB Express

Table 2 Antimicrobial sensitivity, biofilm formation and efflux pump patterns of K. pneumoniae strains

From: Antibiotic resistance, virulence-associated genes analysis and molecular typing of Klebsiella pneumoniae strains recovered from clinical samples

Isolates code	Antibiotic resistant pattern	Anti-biotype (AB)	MDR	Biofilm former	Quantitative biofilm formation	Phenotypic efflux pump
K10, K17, K23, K73, K92, K98	CTX, CAZ, CRO, FOX, NA, CP, FM, TE, S, GM	AB1	+	+	2.63 ± 0.14	+
K15, K20	CTX, CAZ, CRO, FOX, NA, CP, FM, TMP	AB2	+	−	0.025 ± 0.03	+
K1, K6, K13, K25	CTX, CAZ, CRO, FOX, TMP, GM, S	AB 3	+	+	2.13 ± 0.19	+
K4, K12, K21, K74, K77, K94	CAZ, FOX, FM, TE, TMP, S	AB 4	+	+	3.52 ± 0.21	+
K18, K35, K49	CTX, CAZ, CRO, FOX, FM, TMP	AB 5	+	+	0.76 ± 0.06	+
K3, K16, K22	CTX, CAZ, CRO, NA, CP	AB 6	+	+	0.38 ± 0.08	+
K8, K45, K75	CTX, CAZ, CRO, FOX, NA, CP, FM, TE	AB 7	+	+	2.69 ± 0.17	+
K5, K41, K76	CTX, CAZ, CRO, FOX, NA, CP, AMC, CF, S, FM, TMP, IMP, GM, MEN	AB 8	+	+	3.4 ± 0.12	+
K19, K31, K72	CTX, CAZ, CRO, NA, CP, FM, TMP, GM, S	AB 9	+	+	1.8 ± 0.07	−
K7	AMC, S, CF, TMP	AB 10	+	+	0.17 ± 0.16	+
K9, K28, K87	FM, CF, AMC, K, GM, TMP, CP, AN, FOX, CTX, CRO, CAZ	AB 11	+	+	0.81 ± 0.007	+
K24, K26, K40	S, CF, AMC, FM, IPM, TMP, MEN, NA, CP	AB 12	+	−	0.16 ± 0.003	+
K14, K39	CL, TE, PB, AN, TMP, GM, K, S, FM, AMC, CF	AB 13	+	+	0.15 ± 0.006	+
K41, K59, K61, K93	AMC, CF, FM, PB, CL, TE	AB 14	+	+	0.94 ± 0.007	−
K36, K43	CP, TE, NA, FM, MEN, TMP, CF, AMC	AB 15	+	+	0.16 ± 0.006	+
K53, K81, K96	CF, AMC, MEN, TMP, IPM, CP, NA	AB 16	+	+	0.20 ± 0.13	+
K27, K30, K62, K88	FM, AMC, CF, IPM, AN, MEN, GM, TMP, CP, TE, NA, CL	AB 17	+	+	0.19 ± 0.001	+
K2, K11, K60, K78, K100	CF, AMC, TMP, CP, TE, NA	AB 18	+	+	0.13 ± 0.006	+
K50, K80, K85, K86	AMC, FM, CF, CP, TE, NA, MEN, IPM, TMP, GM, AN	AB 19	+	+	2.13 ± 0.003	+
K48, K52, K58, K65	AMC, S, CF, FM, IPM, MEN, CP, NA	AB 20	+	+	3.82 ± 0.009	+
K33, K47, K71, K56, K83, K69	CF, K, FM, AMC, GM, MEN, IPM, AN, TMP, NA, TE, CP	AB 21	+	+	0.19 ± 0.007	+
K 34, K 42, K 99	AMC, CF, FM, IMP, MEN, TMP, CP, NA, TE	AB 22	+	+	1.45 ± 0.008	−
K44, K50, K 54, K7, K66, K 79, K 97, K 63, K 64, K 70, K 82	CAZ, CRO, FOX, K, FM, AMC, CF, AN, TMP, GM, IMP, MEN, CP, TE, NA	AB 23	+	−	0.02 ± 0.002	+
K 29, K 32, K 51, K 55, K 57, K 68, K 84	CP, TE, NA, TMP, GM, IMP, MEN, AMC, FM, CF, CAZ, CTX, CRO, FOX	AB 24	+	−	0.029 ± 0.001	+
K 30, K 89, K 90, K 91, K 37, K 38, K 46, K 95	CF, AMC	AB 25	−	+	0.56 ± 0.001	+

CF Chloramphenicol, AMC Amoxicillin–clavulanic acid, FOX Cefoxitin, CRO Cefteriaxon, CTX Cefotaxime, CAZ Ceftazidime, FM Nitrofurantoin, MEN Meropenem, IMP Imipenem, GM Gentamycin, TMP Trimethoprim–sulfamethoxazole, NA Nalidixic acid, TE Tetracycline, CP Ciprofloxacin, S Streptomycin, K Kanamycin, CL Clindamycin, PB Polymixin B, S Streptomycin

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