Fig. 2

A segment of structure-based protein sequence alignment of α-N-acetylglucosaminidases including hNAGLU (GenBank accession no. AAB06188.1), CpGH89 (GenBank accession no. ABG84150.1), Bf0576 (GenBank accession no. CAH06355.1), Bt0438 (GenBank Accession No. AAO75545.1), and Bt3590 (GenBank Accession No. AAO78695.1). The Trp685-containing extra loop in CpGH89 structure and the corresponding predicted loop in Bf0576 structural model are shown in the red square