Down-regulation of biofilm-associated genes in mecA-positive methicillin-resistant S. aureus treated with M. communis extract and its antibacterial activity

AMB Express

Table 5 Biofilm formation capability and presence/absence of genes associated with biofilm formation in MRSA strains isolated from clinical specimens

Strains	Biofilm formation	Presence of biofilm associated-genes
Strains	Biofilm formation	icaA	icaD	bap〹	SarA
Sa5	+++	+	+	+	+
Sa8	+++	+	+	–	–
Sa12	+++	+	+	+	+
Sa14	+++	+	+	−	+
Sa19	+	–	–	–	+
Sa21	++	+	–	–	+
+++: strong biofilm formation (OD492 > 1.2), ++: medium-positive biofilm formation (1.2˃ OD492 > 0.6) and +: weak biofilm formation (0.6 ˃OD492 > 0.3).