Table 3 Mutations discovered in evolved strains K1–K9
Genome position | Gene/IGR | Annotation/Product | Mutation | Variant ratio |
|---|---|---|---|---|
Del514815A | CGB98_RS02465 | 16S ribosomal RNA | Del461A | 8/9 |
T2052533C | CGB98_RS09630 | HNH endonuclease | T291C | 9/9 |
Del2720013A Del2720032T | CGB98_RS12800 | IS6 family transposase | Del105T Del86A | 7/9 |
In519737T | CGB98_RS02475-02480 | 5S ribosomal RNA copy B (rrf) and putative succinyl diaminopimelate transaminase (dapC), respectively | In-111T of dapC | 8/9 |
A1791301G | CGB98_RS08395-08400 | Peptidoglycan endopeptidase and cytochrome bc complex cytochrome b subunit, respectively | T-476C of RS08395 | 4/9 |
Del2206093A | CGB98_RS10415-10420 | ABC transporter ATP-binding protein and 5S ribosomal RNA (rrf), respectively | Del-235T of RS10415 | 9/9 |
T2231742G | CGB98_RS10555-10560 | tRNA-Lys and succinate CoA transferase (actA), respectively | A+20C of actA | 4/9 |
Del2309538T | CGB98_RS10915-10920 | Hypothetical protein and FAD-binding protein, respectively | Del+159A of RS10920 | 9/9 |