Fig. 3From: Programming adaptive laboratory evolution of 4-hydroxyisoleucine production driven by a lysine biosensor in Corynebacterium glutamicumThe 4-HIL production of preliminary screening strains in 24 deep-well plates after fermented for 96 h. SZ06 was used as the control strain. a The distribution of relative 4-HIL production of mutant strains obtained by eight rounds or three rounds’ evolution. b mutant strains with a relative titer higher than 160%, MK1 − MK4 from the eighth round and MK5 − MK9 from the third round, respectivelyBack to article page