Fig. 4

Immunohistochemistry of tumor tissue. a HE staining of tumor tissue. There were many tumor infiltrating lymphocytes in iturin A group. Expressions of b Ki67, c TGF-β1, and d PDL1 in tumor tissue. Blue indicates the nucleus, and red indicates the target proteins. The scale bar is 50 μm. e Ratio of positive cells. There were significant differences in the expression of Ki67 and TGF-β1. Data are represented as the mean of each group + SD. * indicates that the iturin A group was significantly different compared with the control (n = 3, p < 0.05)