Fig. 3
From: Design of a novel antimicrobial peptide 1018M targeted ppGpp to inhibit MRSA biofilm formation
Effects of 1018M on cell wall and membrane. a–b Scanning electron microscopy (a) and transmission electron microscopy (b) analysis of MRSA ATCC43300 cells treated with IDR-1018 and 1018M. c–d Flow cytometric analysis of PI-staining in MRSA ATCC43300 cells treated with 2× or 4× MIC IDR-1018 (c) and 1018M (d) for 30 or 120 min, respectively. Red line: no peptide, negative control; Blue line: treatment with 1×MIC peptides for 30 min; Orange line: treatment with 2×MIC peptides for 30 min; Green line: treatment with 4×MIC peptides for 30 min. black line: treatment with 1×MIC peptides for 120 min; brown line: treatment with 2×MIC peptides for 120 min; purple line: treatment with 4×MIC peptides for 120 min