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Table 5 Central composite design: terms and the corresponding coefficients

From: Orchestration an extracellular lipase production from Aspergillus niger MYA 135: biomass morphology and fungal physiology

Term Coefficient p-value
Constant 195.0 < 0.001
Linear < 0.001
 X1 (N:C ratio) − 61.9 < 0.001
 X2 (FeCl3) 12.7 0.251
 X3 (Olive oil) 48.8 < 0.001
Interaction < 0.001
 X1X2 28.1 0.057
 X1X3 − 10.9 0.450
 X2X3 39.8 0.009
Quadratic 0.015
 X12 − 64.3 < 0.001
 X22 30.7 0.007
 X32 − 9.7 0.368
Lack-of-fit 0.578
 R2 (%) 80.10  
 R2adj (%) 73.24