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Table 4 Increased glycolysis by deletion kcs1 in the recombinant strain Ymls1Δkcs1ΔGAPmK further improved SAM production

From: Increasing glycolysis by deletion of kcs1 and arg82 improved S-adenosyl-l-methionine production in Saccharomyces cerevisiae

 

2842

Ymls1â–³GAPmK

Ymls1Δkcs1ΔGAPmK

SAM (g L−1)

0.66 ± 0.06

2.22 ± 0.11***

2.89 ± 0.10***

DCW (g L−1)

7.85 ± 0.59

6.54 ± 0.26***

6.35 ± 0.21***

SAM yield to DCW (mg g−1)

84.1

339.4***

455.1***

SAM yield to carbon source (mg g−1)

13.2

44.4***

57.8***

  1. The symbol *** denotes significant diferences between the recombinant strain and the wild strain, with p < 0.001
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