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Table 4 Increased glycolysis by deletion kcs1 in the recombinant strain Ymls1Δkcs1ΔGAPmK further improved SAM production

From: Increasing glycolysis by deletion of kcs1 and arg82 improved S-adenosyl-l-methionine production in Saccharomyces cerevisiae

  2842 Ymls1△GAPmK Ymls1Δkcs1ΔGAPmK
SAM (g L−1) 0.66 ± 0.06 2.22 ± 0.11*** 2.89 ± 0.10***
DCW (g L−1) 7.85 ± 0.59 6.54 ± 0.26*** 6.35 ± 0.21***
SAM yield to DCW (mg g−1) 84.1 339.4*** 455.1***
SAM yield to carbon source (mg g−1) 13.2 44.4*** 57.8***
  1. The symbol *** denotes significant diferences between the recombinant strain and the wild strain, with p < 0.001
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