Fig. 6

Effect of mangiferin on the mRNA and protein expression of TIMP-1/2 and MMP-2/9 in osteosarcoma cells. Cells were incubated with mangiferin (25–100 µM) for 72 h. a Represents the mRNA expression in Saos-2 cells and b mRNA expression in U2OS cells. c Western blot bands in Saos-2 cells and d densitometry analysis of C. N = 6. Control vs. *P < 0.05