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Table 5 Results of studies on the penetration of active substances through pig skin and the amounts of extracted active ingredients accumulated in it

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound

Mass of substance in the acceptor fluid after 24 h of penetration

(µg)

Concentration of substance extracted from the skin

(µg/cm2 skin)

Eugenol*

272.89 ± 54.64ab

566.93 ± 33.34a

EDChA*

302.77 ± 1.90b

555.09 ± 53.22a

ETChA*

297.62 ± 24.97b

539.14 ± 40.53a

DChAA*

247.63 ± 16.45ab

750.82 ± 44.62b

TChAA*

210.54 ± 16.45a

799.41 ± 39.99b

  1. * Mean ± S.D. (n = 3), different letters - values are significantly different, mass substance in the acceptor fluid (P < 0.05), concentration of substance extracted from the skin (P < 0.001)
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