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Table 5 Results of studies on the penetration of active substances through pig skin and the amounts of extracted active ingredients accumulated in it

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound Mass of substance in the acceptor fluid after 24 h of penetration
(µg)
Concentration of substance extracted from the skin
(µg/cm2 skin)
Eugenol* 272.89 ± 54.64ab 566.93 ± 33.34a
EDChA* 302.77 ± 1.90b 555.09 ± 53.22a
ETChA* 297.62 ± 24.97b 539.14 ± 40.53a
DChAA* 247.63 ± 16.45ab 750.82 ± 44.62b
TChAA* 210.54 ± 16.45a 799.41 ± 39.99b
  1. * Mean ± S.D. (n = 3), different letters - values are significantly different, mass substance in the acceptor fluid (P < 0.05), concentration of substance extracted from the skin (P < 0.001)