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Table 4 Total polyphenol content in solutions of test compounds applied to the skin, acceptor fluid solutions obtained after 24 h of collection, and solutions obtained after skin extraction

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound Antioxidant activity (Folin–Ciocalteu method):
Solution applied to the skin Acceptor fluid after 24 h of penetration Solution after skin extraction
mmol gallic acid/dm3
Eugenol* 3.84 ± 0.05a 0.27 ± 0.01a 0.41 ± 0.03b
EDChA * 3.27 ± 0.10b 0.22 ± 0.01b 0.58 ± 0.04a
ETChA* 3.35 ± 0.06b 0.25 ± 0.01ab 0.55 ± 0.01a
DChAA No activity No activity No activity
TChAA No activity No activity No activity
  1. * Mean ± S.D. (n = 3), different letters - values are significantly different, mass substance in the acceptor fluid (P < 0.001)
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