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Table 3 Antioxidant activity of 1% solutions of the test compounds applied to the skin, acceptor fluid obtained after 24 h of collection, and solutions obtained after skin extraction

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound

Antioxidant activity (ABTS method)

Solution applied to the skin

Acceptor fluid after 24 h of penetration

Solution after skin extraction

mmol TE/dm3

Eugenol*

4.74 ± 0.01a

0.25 ± 0.03a

0.91 ± 0.02c

EDChA *

4.70 ± 0.02a

0.19 ± 0.03a

1.14 ± 0.02a

ETChA*

4.71 ± 0.01a

0.20 ± 0.07a

1.03 ± 0.07b

DChAA

No activity

No activity

No activity

TChAA

No activity

No activity

No activity

  1. * Mean ± S.D. (n = 3), different letters - values are significantly different, mass substance in the acceptor fluid (P < 0.001)