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Table 2 Antioxidant activity of 1% solutions of the test compounds applied to the skin, acceptor fluid obtained after 24 h of collection, and solutions obtained after skin extraction

From: Enhancement of the antioxidant and skin permeation properties of eugenol by the esterification of eugenol to new derivatives

Compound Antioxidant activity (DPPH method)
Solution applied to the skin Acceptor fluid after 24 h of penetration Solution after skin extraction
mmol TE/dm3
Eugenol* 1.23 ± 0.01a 0.08 ± 0.01a 0.22 ± 0.02b
EDChA * 1.08 ± 0.02b 0.07 ± 0.00a 0.25 ± 0.01a
ETChA* 1.04 ± 0.01c 0.06 ± 0.00a 0.21 ± 0.01b
DChAA No activity No activity No activity
TChAA No activity No activity No activity
  1. * Mean ± S.D. (n = 3), different letters - values are significantly different, mass substance in the acceptor fluid (P < 0.001)