New perspectives of purple starthistle (Centaurea calcitrapa) leaf extracts: phytochemical analysis, cytotoxicity and antimicrobial activity

AMB Express

Table 3 Minimum inhibitory (MIC) and minimum bactericidal concentration (MBC) of C. calcitrapa extracts

Bacterial strains	MeOH	EtOH	EtOAc	Me₂CO	DCM:MeOH	Str	Van
Bacterial strains	MIC
E. coli ATCC 25922	375	–	200	375	375	4.6	500
MRSA ATCC 33591	15	60	15	7.8	31	–	–
S. aureus ATCC 25923	94	125	16	31	62.5	9	1.6
A. tumefaciens	500	750	250	375	250	–	–
E. amylovora NCPPB 683	200	375	13	375	150	3	400
P. syringae pv. aptata P29	250	500	100	500	250	1.5	–
P. syringae pv. syringae GSPB 1142	200	200	13	150	100	3	–
X. campestris pv. campestris NCPPB 583	200	500	25	150	25	12.5	12.5
	MBC
E. coli ATCC 25922	500	–	250	500	500	6	100
MRSA ATCC 33591	1000	–	1000	500	500	–	–
S. aureus ATCC 25923	125	250	125	125	250	25	3
A. tumefaciens	1000	1000	500	1000	1000	–	–
E. amylovora NCPPB 683	500	500	25	500	200	6	–
P. syringae pv. aptata P29	–	–	500	–	500	6	–
P. syringae pv. syringae GSPB 1142	500	500	25	200	200	6	–
X. campestris pv. campestris NCPPB 583	500	–	150	500	500	25	25

Str—streptomycin; Van—vancomycin. (–) ─ not detected in the range of tested concentrations. Values are expressed in µg/mL