Fig. 6
From: Rhein laden pH-responsive polymeric nanoparticles for treatment of osteoarthritis
PLGA-NPs and Rh-PLGA-NPs@NH4 effect on a IL-1β (*p < 0.01; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs, #p < 0.001; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs). b TNFα (*p < 0.05; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs, #p < 0.05; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs) and c ROS levels (*p < 0.05; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs, #p < 0.01; Rh-PLGA-NPs@NH4 vs. Rh-PLGA-NPs). Data represent the mean ± SD (N = 03)