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Table 2 Berberine potently inhibited infection of HIV-1 Env-pseudotyped viruses

From: Identification of the natural product berberine as an antiviral drug

Virus Clade Tropism IC50 (µg/ml)
T20 Berberine
IIIB B X4 0.193 ± 0.024 6.356 ± 0.336
NL4-3 B X4 0.197 ± 0.035 5.574 ± 0.172
Bal B R5 0.18 ± 0.021 5.586 ± 0.652
JRFL B R5 0.58 ± 0.26 10.275 ± 1.215
JRCSF B R5 0.484 ± 0.131 7.559 ± 0.646
AD8 B R5 0.607 ± 0.12 7.532 ± 0.454