Table 2 Berberine potently inhibited infection of HIV-1 Env-pseudotyped viruses
From: Identification of the natural product berberine as an antiviral drug
Virus | Clade | Tropism | IC50 (µg/ml) | |
|---|---|---|---|---|
T20 | Berberine | |||
IIIB | B | X4 | 0.193 ± 0.024 | 6.356 ± 0.336 |
NL4-3 | B | X4 | 0.197 ± 0.035 | 5.574 ± 0.172 |
Bal | B | R5 | 0.18 ± 0.021 | 5.586 ± 0.652 |
JRFL | B | R5 | 0.58 ± 0.26 | 10.275 ± 1.215 |
JRCSF | B | R5 | 0.484 ± 0.131 | 7.559 ± 0.646 |
AD8 | B | R5 | 0.607 ± 0.12 | 7.532 ± 0.454 |