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Fig. 6 | AMB Express

Fig. 6

From: Production of dengue virus-like particles serotype-3 in silkworm larvae and their ability to elicit a humoral immune response in mice

Fig. 6

a The interactions between DENV-LPs/3CprME and /3prME with sera from mice immunized with the DENV tetravalent DNA vaccine and mixed sera from dengue patients [NS1(+), RT-PCR (+)] were investigated. Binding reactions were analyzed using direct ELISA as described (Welch t-test, **p < 0.01). Specific IgG generation by DENV-LPs/3CprME (b) and /3prME (c). BALB/c mice were intraperitoneally immunized with 50 μg monovalent DENV-LPs/3CprME and/3prME. At 2 and 4 weeks, sera were collected and analyzed for specific IgGs (Welch t-test, *p < 0.05, **p < 0.01)

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