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Fig. 4 | AMB Express

Fig. 4

From: Mukonal exerts anticancer effects on the human breast cancer cells by inducing autophagy and apoptosis and inhibits the tumor growth in vivo

Fig. 4

a TEM analysis of SK-BR-3 cells after being exposed to indicated doses of mukonal. Results revealed formation of autophagic vesicles/autophagosomes in treated groups as compared to control group. Autophagosomes have been shown by arrows in the picture. b TEM analysis of MDA-MB-231 cells after being exposed to indicated doses of mukonal. Results revealed formation of autophagic vesicles/autophagosomes in treated groups as compared to control group. Autophagosomes have been shown by arrows in the picture. c Western blotting results of SK-BR-3 cells after being exposed to mukonal at indicated doses. In treated groups enhanced activity of Beclin-1, LC3B-I and LC3B-II was observed with increasing concentrations of mukonal. d Western blotting results of MDA-MB-231 cells after being exposed to mukonal at indicated doses. In treated groups enhanced activity of Beclin-1, LC3B-I and LC3B-II was observed with increasing concentrations of mukonal

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