Fig. 1

Skin testing with recombinant proteins. Healthy, BCG immunized individuals (n = 95) and TB patients, either negative (n = 40) or positive (n = 38) for HIV infection, were intradermally inoculated with 5 TU of Tubersol PPD Tuberculin or the bioequivalent 1 µg of DPPD. Induration was measured 24 h later. Results were determined to be positive when, consistent with CDC guidelines, induration > 10 mm in HIV negative individuals and > 5 mm in HIV positive individuals. In A, each dot represents an individual data point, while the solid line represents the correlation of results and the black dotted lines represent the 95% confidence intervals. The r² value is indicated in the text insert. In B, per cent of each group falling within the indicated induration range is plotted