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AMB Express
Fig. 5 | AMB Express

Fig. 5

From: Synthesis of cyclophosphamide metabolites by a peroxygenase from Marasmius rotula for toxicological studies on human cancer cells

Fig. 5

Genotoxicity of CPA, PPA or 4-OH-CPAUPO on HepG2 and MCF-7 cells. Cells were treated with different concentrations of the respective compounds for 24 h. γH2AX foci formation was determined using indirect immunofluorescence (pink). Nuclei were stained with DAPI (blue). Representative images of (a) HepG2 and (b) MCF-7 nuclei are shown as obtained with Olympus IX81 fluorescence microscope and 100 × objective (scale bar 5 µm)

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