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Table 4 Effects of nisin/glabridin, nisin/licoricidin, and nisin/licochalcone A on the killing of a pre-formed E. faecalis ATCC 19433 biofilm after a 30-min contact

From: Biocompatible combinations of nisin and licorice polyphenols exert synergistic bactericidal effects against Enterococcus faecalis and inhibit NF-κB activation in monocytes

Compound % biofilm killing
None (PBS treatment) 0
Nisin (12.5 µg/mL) + Glabridin (25 µg/mL) 61.4 ± 6.0*
Nisin (12.5 µg/mL) + Licoricidin (6.25 µg/mL) 75.8 ± 3.1*
Nisin (12.5 µg/mL) + Licochalcone A (12.5 µg/mL) 76.4 ± 3.0*
  1. *Significantly different (p < 0.01) from control biofilms treated with PBS
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