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Table 4 Effects of nisin/glabridin, nisin/licoricidin, and nisin/licochalcone A on the killing of a pre-formed E. faecalis ATCC 19433 biofilm after a 30-min contact

From: Biocompatible combinations of nisin and licorice polyphenols exert synergistic bactericidal effects against Enterococcus faecalis and inhibit NF-κB activation in monocytes

Compound

% biofilm killing

None (PBS treatment)

0

Nisin (12.5 µg/mL) + Glabridin (25 µg/mL)

61.4 ± 6.0*

Nisin (12.5 µg/mL) + Licoricidin (6.25 µg/mL)

75.8 ± 3.1*

Nisin (12.5 µg/mL) + Licochalcone A (12.5 µg/mL)

76.4 ± 3.0*

  1. *Significantly different (p < 0.01) from control biofilms treated with PBS