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Table 3 Fractional inhibitory concentration index (FICI) values for combinations of nisin and licorice polyphenols against E. faecalis ATCC 19433

From: Biocompatible combinations of nisin and licorice polyphenols exert synergistic bactericidal effects against Enterococcus faecalis and inhibit NF-κB activation in monocytes

Compound A

Compound B

FICI*

Effect

Nisin

Glabridin

0.09

Synergistic

Nisin

Licoricidin

0.25

Synergistic

Nisin

Licochalcone A

0.5

Synergistic

  1. *FICI ≤ 0.5: synergistic effect; FICI > 0.5 and ≤ 4.0: no effect; FICI > 4.0: antagonistic effect
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