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Table 6 ELD50 and ELD50 of the progeny strains

From: Effect of the selection pressure of vaccine antibodies on evolution of H9N2 avian influenza virus in chickens

Immune status Tissue Strains Mutations EID50 ELD50
HA NA PB2 NP NS1 M1
Immunized Trachea V1 K131R, A198T, L234Q Amino acids 67–76 deletion R318K, R355K – – – 6.9 0
Immunized Lung V2 K131R, A168T, A198T, L234Q Amino acids 67–76 deletion R318K – – – 7 0
Immunized Trachea V3 K131R, N201D, A198T, L234Q Amino acids 67–76 deletion – – – – 7.2 0
Immunized Lung V4 K131R, A198T, L234Q Amino acids 67–76 deletion R318K, R355K – – – 7 0
Immunized Lung V5 K131R, A198T, L234Q Amino acids 67–76 deletion – – – – 7 0
Nonimmunized Trachea N1 A198V, M224K, Q234L, L281F, N285D – R318K V186I, L466I L77I F62L 9.5 7.4
Nonimmunized Trachea N2 A198V, M224K, Q234L, N285D – R318K V186I, L466I L77I F62L 9.6 7.3
Nonimmunized Lung N3 A198V, M224K, Q234L, L281F, N285D – R318K V186I, L466I L77I F62L 9.1 7.2
Nonimmunized Lung N4 E114K, A198V, M224K, Q234L, L281F, N285D – R318K V186I, L466I L77I F62L 9.8 7.5
Nonimmunized Trachea N5 A198V, M224K, Q234L, L281F, N285D – R318K V186I, L466I L77I F62L 9.4 7.4
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