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AMB Express
Fig. 2 | AMB Express

Fig. 2

From: MicroRNA-466c-3p exerts protective effect on neuronal apoptosis and improves functional recovery post spinal cord injury via mitochondrial apoptotic pathway

Fig. 2

a Expression of miR-466c-3p was determined by qRT-PCR reaction on the 1st, 7th, 14th and the 28th day after inducing spinal cord injury followed by treatment of miR-466c-3p mimics. *P < 0.05, **P < 0.01 compared to respective miR-inhibitor negative control. b Outcomes of BBB analysis for evaluation of locomotor activity on the 1st, 7th, 14th and the 28th day after inducing spinal cord injury after treating the animals with miR-466c-3p agomir. c Results of Immunohistochemical analysis showing expression of cleaved caspase-3 in the spinal tissue after spinal cord injury. *P < 0.05, **P < 0.01 compared to sham operated animals; ##P < 0.01 compared to SCI rats. d Results of TUNEL assay for studying the apoptosis in the cells after 14 days of inducing spinal cord injury. The results are mean ± SD

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