Fig. 4
From: Metabolic enzyme clustering by coiled coils improves the biosynthesis of resveratrol and mevalonate
The clustering of biosynthetic enzymes via coiled-coil-forming domains improves resveratrol production in E. coli. a Enhancement of resveratrol biosynthesis in E. coli after 8 h, depending on the type of coiled-coil-forming domain fused to the enzymes. Simultaneously expressed native enzymes (4CL + STS) served as a reference. b The expression of enzymes coupled via coiled-coil-forming domain fusion was determined by WB. The same protein expression in three representative fermentations is shown in Additional file 1: Fig. S2