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Table 2 Organs index of rats treated with 5-HMF and DHMF (g/100 g of body weight)

From: Biotransformation of 5-hydroxymethylfurfural into 2,5-dihydroxymethylfuran by Ganoderma sessile and toxicological assessment of both compounds

Organs	A	B	C	D	E
Liver	3.12 ± 0.31	3.06 ± 0.19	3.04 ± 0.26	2.83 ± 0.09	3.05 ± 0.17
Spleen	0.22 ± 0.01	0.25 ± 0.01	0.22 ± 0.04	0.25 ± 0.06	0.22 ± 0.02
Kidney	0.73 ± 0.06	0.75 ± 0.06	0.75 ± 0.07	0.75 ± 0.07	0.75 ± 0.06
Lung	0.50 ± 0.02	0.52 ± 0.02	0.47 ± 0.01	0.51 ± 0.04	0.49 ± 0.03
Heart	0.34 ± 0.01	0.35 ± 0.03	0.32 ± 0.02	0.33 ± 0.02	0.32 ± 0.04
Brain	0.79 ± 0.05	0.74 ± 0.02	0.68 ± 0.09	0.74 ± 0.05	0.79 ± 0.07

Values represented as mean ± SD and analyzed by one-way ANOVA with S–N–K test. P > 0.05 vs. control group, n = 6 of A, D and E groups, n = 3 of B and C groups. A: Distilled water (0 mg/kg); B: 5-HMF (300 mg/kg); C: DHMF (300 mg/kg); D: 5-HMF (2000 mg/kg); E: DHMF (2000 mg/kg)

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