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Table 2 Organs index of rats treated with 5-HMF and DHMF (g/100 g of body weight)

From: Biotransformation of 5-hydroxymethylfurfural into 2,5-dihydroxymethylfuran by Ganoderma sessile and toxicological assessment of both compounds

OrgansABCDE
Liver3.12 ± 0.313.06 ± 0.193.04 ± 0.262.83 ± 0.093.05 ± 0.17
Spleen0.22 ± 0.010.25 ± 0.010.22 ± 0.040.25 ± 0.060.22 ± 0.02
Kidney0.73 ± 0.060.75 ± 0.060.75 ± 0.070.75 ± 0.070.75 ± 0.06
Lung0.50 ± 0.020.52 ± 0.020.47 ± 0.010.51 ± 0.040.49 ± 0.03
Heart0.34 ± 0.010.35 ± 0.030.32 ± 0.020.33 ± 0.020.32 ± 0.04
Brain0.79 ± 0.050.74 ± 0.020.68 ± 0.090.74 ± 0.050.79 ± 0.07
  1. Values represented as mean ± SD and analyzed by one-way ANOVA with S–N–K test. P > 0.05 vs. control group, n = 6 of A, D and E groups, n = 3 of B and C groups. A: Distilled water (0 mg/kg); B: 5-HMF (300 mg/kg); C: DHMF (300 mg/kg); D: 5-HMF (2000 mg/kg); E: DHMF (2000 mg/kg)