Fig. 4
From: Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells
Cytotoxic effect of the S. typhimurium VNP 20009 expressing Laz (VNP-Laz) on tumor cells in vitro. Monolayers glioblastoma cell line LN-229 (WT p53) were co-cultured with increasing bacterial densities (104, 106, or 108 cfu) of VNP alone or VNP-Laz under hypoxic conditions for 24 h. Apoptosis was assessed the same method of breast cancer cell line for comparison. All data are shown as mean ± s.e.m and represent data from three independent experiments n = 3. *P < 0.0001 with respect to the control groups at the same concentration