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Fig. 3 | AMB Express

Fig. 3

From: Bacterial delivery of the anti-tumor azurin-like protein Laz to glioblastoma cells

Fig. 3

Cytotoxic effect of the S. typhimurium VNP20009 expressing Laz (VNP-Laz) on tumor cells in vitro. Monolayers of breast cancer cells MCF-7 were co-cultured with increasing bacterial densities (104, 106, or 108 cfu) of VNP alone or VNP-Laz under hypoxic conditions for 24 h. Apoptosis was assessed using caspase 3, 7 homogenate assay. All data are shown as mean ± s.e.m and represent data from three independent experiments n = 3. *P < 0.0001 with respect to the control groups at the same concentration

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