Skip to main content

Table 1 Effect of myricitrin on fasting lipid profile and aortic wall area percent (mm2) after 45 days of high cholesterol diet (HCD) fed rats treated with myricitrin at dosages of 1, 10 and 100 μM

From: Myricitrin exhibits anti-atherosclerotic and anti-hyperlipidemic effects in diet-induced hypercholesterolemic rats

GroupsCholesterol
(mg/dl)
HDL (mg/dlLDL (mg/dl)TG (mg/dl)Aortic wall area percent (mm2)Percent of aortic wall area changes
Sham (normal diet)37.2 ± 1.619.5 ± 1.110.9 ± 0.755.6 ± 3.60.205 ± 0.017 
Control (1% HCD)1134.5 ± 25.3***4.2 ± 0.1***957.3 ± 15.4***97.5 ± 6.2**0.298 ± 0.019*14.5% ↑
Compared with sham
1 μM of myricitrin + 1% of HCD965.2 ± 17.2#5.1 ± 0.1#916.6 ± 17.1#92.3 ± 5.80.291 ± 0.0212.3% ↓
Compared with control
10 μM of myricitrin + 1% of HCD711.8 ± 16.4##11.1 ± 1.1#651.7 ± 11.5#81.7 ± 5.60.286 0.015#4% ↓
Compared with control
100 μM of myricitrin + 1% of HCD427.1 ± 11.2###17.5 ± 1.2###213.5 ± 8.6###73.4 ± 4.4#0.216 0.011#27.5% ↓
Compared with control
Positive control (10 mg/kg body weight of atorvastatine)213.4 ± 7.8###18.5 ± 1.3###327.8 ± 7.2###76.5 ± 3.7#0.272 0.016#8.7% ↓
Compared with control
  1. Values are expressed as mean with standard deviations (SD). P < 0.05 was considered as statistically significant
  2. *** P < 0.001 vs. sham group
  3. #P < 0.05, ## P < 0.01 and ### P < 0.01 vs. control group