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Table 2 The protection ratio of the subunit vaccine prepared by the PCV2-VLPs produced in different processes for the PCV2 virus infection in mice

From: Development of a simple and high-yielding fed-batch process for the production of porcine circovirus type 2 virus-like particle subunit vaccine

Production process

Lot

Vaccines

Protection ratio (negative/all)

Batch culture

1

5.5 μg PCV2-VLPs

10/10

2

5.5 μg PCV2-VLPs

10/10

3

5.5 μg PCV2-VLPs

9/10

Fed-batch culture

1

5.5 μg PCV2-VLPs

9/10

2

5.5 μg PCV2-VLPs

9/10

3

5.5 μg PCV2-VLPs

10/10

Positive control

1

Commercial inactived vaccine

9/10

Negative control

1

Sf9 cells infected by wild baculovirus

2/10

Blank control

1

PBS

2/10