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AMB Express

Table 2 Transcytosis rate of scFab-ANG and scFab

From: Recombinant expressing angiopep-2 fused anti-VEGF single chain Fab (scFab) could cross blood–brain barrier and target glioma

Protein

Concentration (μg/mL)

Transcytosis rate (μg/cm2/h)

 

200

0.129 ± 0.0042

scFab-ANG

100

0.111 ± 0.0038

 

50

0.0284 ± 0.00056

scFab

200

0.0477 ± 0.00068

  1. The concentrations of scFab-ANG and scFab in lower chambers were measured every 30 min. Transcytosis curve was generated, X-axis was time, Y-axis was transcytosis. Transcytosis rate was calculated as curve slope
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